THE LATEST RESEARCH ON COFFEE AND HEALTH
A Lafranconi et al performed a comprehensive meta-analysis of the association between coffee consumption and risk of endometrial cancer. In 12 eligible studies, the dose-response relationship, as well as the risk of endometrial cancer for the highest versus the lowest categories of coffee consumption, were assessed. Subgroup analyses considering menopausal and receptor statuses, smoking status, and BMI (Body Mass Index) were performed in order to identify potential cofounders. Findings suggest that increased coffee consumption is associated with decreased risk of endometrial cancer, and this association was also observed for postmenopausal cancer.
A Lafranconi et al, 2017. Coffee Decreases the Risk of Endometrial Cancer: A Dose-Response Meta-Analysis of Prospective Cohort Studies, Nutrients, Volume 9 (11).
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C L R S Paiva et al performed a systematic review summarising the effects of coffee or coffee components on serum levels of inflammatory markers. 15 studies (eight involving coffee and seven caffeine) were included. Increased adiponectin levels were found in four of seven trials comparing filtered coffee/caffeinated coffee with placebo or comparing its levels at baseline and after consumption of medium or dark roasted coffee, but no change was seen in caffeine trials. None of the five studies assessing the effects of coffee found changes in C-reactive protein (CPR), but one out of three trials found decreased CPR levels in response to caffeine. These data suggest a predominant
anti-inflammatory action of coffee but not of caffeine consumption. Moreover, the proinflammatory and anti-inflammatory responses to caffeine point to its complex effects on the inflammatory response.
C L R S Paiva et al, 2017. Consumption of coffee or caffeine and serum concentration of inflammatory markers: a systematic review, Critical Reviews in Food Science and Nutrition, published online.
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