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The available scientific evidence does not support a relationship between caffeine consumption and adverse reproductive or perinatal outcomes. The studies available from the last decade do not provide convincing evidence that moderate caffeine consumption (200mg per day from all sources, not only coffee) increases the risk of any reproductive complication.

On the whole, associations with subfecundity, preterm delivery and congenital malformations are not routinely observed. Studies of pregnancy loss and fetal growth have generated more interest due to the frequency with which adverse effects are reported in connection with caffeine use.

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