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Cancer in Europe
According to data from the World Health Organization (WHO), cancer causes 20% of deaths in Europe3. With more than 3 million new cases and 1.7 million deaths each year, cancer is the most significant cause of death and morbidity in Europe after cardiovascular disease3.Europe comprises only one eighth of the total world population but has around one quarter of global cancer cases: some 3.2 million new patients per year3. The most common cancers in Europe in 2012 were breast, prostate, bowel and lung, which together accounted for around 40% of all cancer cases4.
Coffee and cancer risk
In 2016, IARC included a large number of new studies in an updated review of the scientific research related to coffee and cancer. As a result of this review, IARC downgraded the classification of coffee from Group 2B to Group 3, for agents “not classifiable as to carcinogenicity to humans”1. IARC’s 2016 review found no clear association between coffee intake and cancer at any body site. IARC’s review also found that reduced risks were seen for cancers of the liver and uterine endometrium1.
Comprehensive reviews of the data concerning coffee drinking and the risk of cancer at various sites have also been undertaken5-12,13,14. One, a 2011 meta-analysis of 40 prospective cohort studies, including over 2 million participants across Europe, North America and Asia, which assessed the association between coffee intake and cancer risk in humans quantitatively, found that coffee consumption was not associated with an increased risk of cancer8. A 2017 meta-analysis also concluded that coffee consumption was not associated with overall cancer risk 13. For some types of cancer, coffee intake was inversely associated with disease risk. A meta-analysis of observational studies published in 2016 concluded that coffee consumption was inversely associated with risk of oral, pharyngeal, colon, liver, prostate, and endometrial cancer risk and of risk of melanoma, but associated with an increased risk of lung cancer14.A large Japanese cohort study also found no association between coffee consumption and increased risk of total cancer mortality15.
In its Scientific Opinion on the Safety of Caffeine, published in 2015, The European Food Safety Authority concluded that: “caffeine intakes from all sources up to 400mg per day (about 5.7mg/kg bw per day for a 70kg adult) consumed throughout the day do not give rise to safety concerns for healthy adults in the general population. No health concerns in relation to acute toxicity, bone status, cardiovascular health, cancer risk or male fertility have been raised by other bodies in previous assessments for this level of habitual caffeine consumption and no new data have become available on these or other clinical outcomes which could justify modifying these conclusions”2.
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