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Coffee & Health
Cardiovascular health

The effect of acute cafe latte ingestion on fasting serum lipid levels in healthy individuals

A Zargar et al, 2013
Journal of Clinical Lipidology, published online ahead of print
February 26, 2013


Many patients drink cafe latte as part of their habitual morning routine to start their day and may be unable to skip this step before drawing a fasting blood sample for cholesterol testing. However, it is unknown what the acute effects of consuming a cafe latte are on fasting serum lipids just before blood sampling.


This was a prospective, open-label study with the primary objective of evaluating the acute effect of a 12-oz cafe latte (2% milk) on calculated low-density lipoprotein cholesterol (LDL-C) and secondary objectives of triglyceride, total cholesterol, high-density lipoprotein cholesterol (HDLC), non-HDL-C, and fasting blood glucose (FBG).


A 10-hour fasting lipid profile was obtained before and 30 minutes after subjects consumed the cafe latte.


Forty-nine adult participants (34 females; age [mean 6 SD] 32.2 ± 13.2 years) were studied. No significant changes in total cholesterol, LDL-C, or non-HDL-C were observed after coffee consumption. Triglyceride significantly decreased from a median of 76.0 to 75.0 mg/dL (P = .002). HDL-C and FBG increased from a mean of 54.4 ± 12.7 to 56.4 ±14.5 mg/dL (P = .015) and 87.2 ± 7.0 to 97.3 ± 12.9 mg/dL (P , .001), respectively.


Consumption of 12 oz. of cafe latte within one hour of blood draw did not result in a significant change in LDL-C or non-HDL-C in young, non obese healthy individuals. However, FBG levels increased by almost 12%.

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