Urgert R& Katan MB. The cholesterol-raising factor from coffee beans. J R Med, 1996,89(11), 618-623

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J R Med, 1996,89(11), 618-623

The cholesterol-raising factor from coffee beans.

Urgert R& Katan MB.

Some coffee brewing techniques raise the serum concentration of total and low-density-lipoprotein cholesterol in humans, whereas others do not. The responsible factors are the diterpene lipids cafestol and kahweol, which make up about 1% (wt:wt) of coffee beans. Diterpenes are extracted by hot water but are retained by a paper filter. This explains why filtered coffee does not affect cholesterol, whereas Scandinavian “boiled,” cafetiere, and Turkish coffees do. We describe the identification of the cholesterol-raising factors, their effects on blood levels of lipids and liver function enzymes, and their impact on public health, based on papers published up to December 1996.

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