Yearly Archives: 2020

J Wirth et al, 2020. A healthy lifestyle pattern and the risk of symptomatic gallstone disease: results from two prospective cohort studies, American Journal of Clinical Nutrition, published online.

ABSTRACT Background:  Symptomatic gallstones cause high financial and disease burden for public health systems. The combined role of diet and other lifestyle factors has not been studied so far. Objectives:  We aimed to investigate the association between an a priori defined healthy lifestyle score (HLS, including healthy diet, moderate alcohol and regular coffee intakes, never […]

A N Georigiou et al, 2020. Cigarette smoking, coffee consumption, alcohol intake, and risk of Crohn’s disease and ulcerative colitis: a mendelian randomization study, Inflammatory Bowel Disease, published online.

ABSTRACT Background:  Crohn’s disease (CD) and ulcerative colitis (UC) are widely associated with smoking in epidemiological studies, whereas there are conflicting results for the association between CD and UC for both coffee and alcohol consumption. Herein, we aimed to investigate whether cigarette smoking and alcohol and coffee consumption are causally associated with either CD or […]

S K Jyvakorpi et al, 2020. Association of coffee drinking with physical performance in the oldest-old community-dwelling men The Helsinki Businessmen Study (HBS), Aging Clinical Experimental Research, published online.

ABSTRACT Background:  Habitual coffee drinking has been associated with lower risk of various chronic diseases linked to poor physical performance. Objective: We explored cross-sectional associations between coffee consumption and physical performance among oldest-old community-dwelling men in the Helsinki Businessmen Study (HBS). Methods:  A random sample of HBS survivors (n = 126, mean age 87 years) […]

G Schepici et al, 2020. Caffeine: An overview of its beneficial effects in experimental models and clinical trials of Parkinson’s disease, International Journal of Molecular Science, Volume 21 (13).

ABSTRACT Parkinson’s Disease (PD) is a neurological disease characterized by the progressive degeneration of the nigrostriatal dopaminergic pathway with consequent loss of neurons in the substantia nigra pars compacta and dopamine depletion. The cytoplasmic inclusions of α-synuclein (α-Syn), known as Lewy bodies, are the cytologic hallmark of PD. The presence of α-Syn aggregates causes mitochondrial […]

M C Cornelis et al, 2020. Recent caffeine drinking associated with cognitive function in the UK Biobank, Nutrients, Volume 12 (7).

ABSTRACT Clinical evidence points to the premise that caffeine may benefit cognition, but whether these findings extend to real life settings and amidst factors that impact caffeine metabolism is unclear. The aim of this study was to investigate the impact of recent caffeine drinking on cognitive ability while additionally accounting for lifestyle and genetic factors […]

Next Page »