Yearly Archives: 2013

V K Dik et al, 2013, Coffee and tea consumption, genotype based CYP1A2 and NAT2 activity, and colorectal cancer risk – results from the EPIC Cohort Study, International Journal of Cancer, published online ahead of print.

Coffee and tea contain numerous antimutagenic and antioxidant components and high levels of caffeine that may protect against colorectal cancer (CRC). We investigated the association between coffee and tea consumption and CRC risk and studied potential effect modification by CYP1A2 and NAT2 genotypes, enzymes involved in the metabolization of caffeine. Data from 477,071 participants (70.2% female) of the […]

S Zhong et al, 2013, Coffee consumption and risk of prostate cancer: an up-to-date meta-analysis, European Journal of Clinical Nutrition published online ahead of print.

Background/Objectives: Epidemiologic findings concerning the association between coffee consumption and prostate cancer risk yielded mixed results. We aimed to investigate the association by performing a meta-analysis of all available studies. Subjects/Methods: We searched PubMed, Web of Science and EMBASE for studies published up to July 2013. We calculated the summary relative risk (RR) and 95% confidence intervals […]

A Discacciati et al, 2013, Coffee consumtpion and risk of nonaggressive, aggressive and fatal prostate cancer – a dose-response meta-analysis, Annals of Oncology, published online ahead of print.

BACKGROUND: Existing epidemiological evidence is controversial regarding the possible associations between coffee consumption and risk of prostate cancer (PCa) by aggressiveness of the disease. MATERIALS AND METHODS: We conducted a random-effects dose-response meta-analysis to assess the relationships between coffee consumption and nonaggressive, aggressive and fatal PCa risk. Studies were identified by a search of Medline […]

Y Jin & E Giovannucci, 2013, Coffee consumption and total mortality: a meta-analysis of twenty prospective studies, British Journal of Nutrition, published online ahead of print.

ABSTRACT Coffee consumption has been shown to be associated with various health outcomes, but no comprehensive review and meta-analysis of the association between coffee consumption and total mortality has been conducted. To quantitatively assess this association, we conducted a meta-analysis of prospective cohort studies. Eligible studies were identified by searching the PubMed and EMBASE databases […]

K Bambha et al, 2013, Coffee consumption in NAFLD patients with lower insulin resistance is associated with lower risk of severe fibrosis, Liver International, published online ahead of print.

BACKGROUND & AIMS: Coffee has inverse relationships with both type 2 diabetes and hepatic fibrosis in patients with nonalcoholic fatty liver disease (NAFLD). Relationships were explored between coffee intake and insulin resistance (IR) with respect to NAFLD histologic severity. METHODS: We analyzed data from 782 adults (≥18 years) in the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) from 2004 […]

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