- The scientific evidence* links coffee consumption with a reduced risk of developing gallbladder disease (or symptomatic gallstones). It is thought that coffee may play a preventive role in their development.
- Coffee may have different effects depending on the stage of gallbladder disease. Coffee, and caffeine, appear to trigger contraction of the gallbladder.
- Increased gallbladder contraction may prevent small crystals becoming large gallstones in early disease, but if large gallstones are present, gallbladder contraction may cause pain.
- More studies are required to elucidate the exact mechanisms behind the effects of coffee consumption on gallbladder disease.
*Very few relevant, and significant, human epidemiological studies on the role of coffee in gallbladder disease have been published since 2002.