Neurodegenerative disorders

Research Overview

At a glance

• Epidemiological studies suggest that a regular, lifelong, moderate consumption of coffee/caffeine may slow down physiological, age-related cognitive decline, especially in women and those over 80 years old in particular.
• Although research suggests that lifelong coffee consumption is linked to a reduced risk of developing Alzheimer’s disease, further studies are warranted before any firm conclusions can be drawn.
• There is a substantial amount of epidemiological research showing that as coffee consumption rises, risk of Parkinson’s disease falls.
  • The evidence suggests a potential preventative effect of coffee on disease development.
  • According to animal studies, it is likely that caffeine in coffee is the main component responsible for the potential preventative effect of coffee.
  • Further research is needed before firm conclusions can be drawn.
• Several recent studies suggest that moderate coffee consumption may also reduce the risk of stroke.
• The mechanisms of action underlying the neuroprotective effects of coffee constituents remain unclear, although caffeine is thought to play a role.